Pretreatment factors
Age (years)
*
<=50
>50
LDH (U/L)
*
<=245
>245
T stage (AJCC/UICC 9th)
*
1
2
3
4
N stage (AJCC/UICC 9th)
*
0
1
2
3
cfEBV DNA copies
*
<=2000
>2000
CNN status
*
No
Yes
Pretreatment factors
Post-IC factors
cfEBV DNA copies
NA
0
>0
Tumor Response
NA
CR/PR
SD/PD
Post-IC factors
Mid-RT factors
cfEBV DNA copies
NA
0
>0
Tumor Response
NA
CR/PR
SD/PD
Mid-RT factors
Post-RT factors
cfEBV DNA copies
NA
0
>0
Tumor Response
NA
CR
Non-CR
Post-RT factors
Pretreatment
Post-IC
Mid-RT
Post-RT
Definitions
CNN - central nodal necrosis
IC - induction chemotherapy
OS - overall survival
PFS - progression-free survival
RAIRI - Response adapted individualized risk index
RT - radiotherapy
Definitions
